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VITAMIN A (RETINOL) SERUM OR PLASMA
SKU:
E740
Test Contains (LOINC)
Vitamin A (Retinol) (2923-1), Vitamin A Ser/Pla - Interpretation (48767-8), Vitamin A (Retinyl Palmitate) (38496-6)
SPECIMEN REQUIREMENTS
Sample Type
Serum or Plasma
Preferred Container
Sodium or Lithium Heparin (Green), Plasma Separator Tube, or Serum Separator Tube
Alternate Container
EDTA (Lavender Top) Tube
Sample Volume
1.0 mL
Minimal Sample Volume
0.2 mL
Handling Instructions
Patient should fast for 12 hours and abstain from alcohol for 24 hours prior to collection. Separate serum or plasma within 1 hour of collection. Transfer 1 mL serum or plasma to a Standard Transport Tube immediately. (Min: 0.2 mL) Avoid hemolysis.
Client Transport Temperature
Refrigerated
Specimen Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 month; Frozen: 1 year
Unsuitable Specimen
Whole blood or body fluids other than serum or plasma.
TESTING
Frequency
Sunday, Monday, Tuesday, Wednesday, Thursday, Friday, Saturday
Expected Turn Around
2 - 5 Days
Responsible Dept
Reference Lab
Referral Lab
ARUP
Referral Lab Code
0080525
CPT
84590
Methodology
Quantitative High Performance Liquid Chromatography
ADDITIONAL INFORMATION
Notes
Serum retinol is typically maintained until hepatic stores are almost depleted. Values greater than 0.30 mg/L represent adequate liver stores, whereas values less than 0.10 mg/L indicate deficiency. Samples that come in contact with plastic tubing or have been exposed to excessive light may show low results.

Vitamin A toxicity occurs when retinol concentration exceeds the capacity of retinol binding protein (RBP). Individuals with compromised renal function can retain RBP and may, therefore, have moderate retinol elevations. Drugs which interfere with vitamin A analysis include probucol (Lorelco).

This assay does not measure other vitamin A metabolites such as retinaldehyde and retinoic acid.